基因名:
SCO2
产品别名:
CEMCOX1; ECGF1; Gliostatin; MC4DN2; MYP6; PD-ECGF; SCO1L; TP; TYMP; TdRPase; SCO2; synthesis of cytochrome C oxidase 2; synthesis of cytochrome C oxidase 2; protein SCO2 homolog, mitochondrial; Platelet-derived endothelial cell growth factor; SCO cytochrome c oxidase assembly protein 2; SCO cytochrome oxidase deficient homolog 2; SCO2, cytochrome c oxidase assembly protein; Thymidine phosphorylase; SCO细胞色素氧化酶缺陷同源物2(SCO2); 细胞色素氧化酶缺失蛋白2;
背景信息:
Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors; this gene encodes one of the COX asembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy. [provided by RefSeq, Dec 2009]