基因名:
HDAC6
产品别名:
CPBHM; HD6; JM21; PPP1R90; HDAC6; histone deacetylase 6; histone deacetylase 6; histone deacetylase 6; protein phosphatase 1, regulatory subunit 90; tubulin-lysine deacetylase HDAC6; 磷酸化组蛋白去乙酰化酶6; 组蛋白去乙酰化酶6; 组蛋白脱乙酰基酶6(HDAC6);
背景信息:
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008].