基因名:
BCL2L10
产品别名:
BCL-B; Boo; Diva; bcl2-L-10; BCL2L10; BCL2 like 10; BCL2 like 10; bcl-2-like protein 10; BCL2-like 10 (apoptosis facilitator); anti-apoptotic protein Boo; anti-apoptotic protein NrH; apoptosis regulator Bcl-B; death inducer binding to vBcl-2 and Apaf-1; BCL2样10促凋亡蛋白;
背景信息:
Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. BCL2L10 is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human BCL2L10 protein is widely expressed. Also, the human BCL2L10 functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1.