基因名：
ABCC5
产品别名：
ABC33； EST277145； MOAT-C； MOATC； MRP5； SMRP； pABC11； ABCC5； ATP binding cassette subfamily C member 5； ATP binding cassette subfamily C member 5； ATP-binding cassette sub-family C member 5； ATP-binding cassette, sub-family C (CFTR/MRP), member 5； canalicular multispecific organic anion transporter C； multi-specific organic anion transporter C； multidrug resistance-associated protein 5； ATP结合盒转运蛋白C5(ABCC5)； 多药耐药相关蛋白5；
背景信息：
MRP5 (190-200 kDa) is closely related to MRP4, both lacking the first five membrane spanning regions. MRP5 is a GS-X multi specific organic anion pump (nucleotide analogs). MRP5 may transport DNP-GS and may be inhibited by certain inhibitors of organic anion transport (sulfinpyrazone). MRP5 may also transport organic anions with the anionic moiety of phosphate/phosphonate group, a function which provides the ability to resist against anti cancer drugs 6-MP and thioguanine as well as the anti-HIV drug PMEA.
