基因名：
SIGMAR1
产品别名：
ALS16； DSMA2； OPRS1； SIG-1R； SR-BP； SR-BP1； SRBP； hSigmaR1； sigma1R； SIGMAR1； sigma non-opioid intracellular receptor 1； sigma non-opioid intracellular receptor 1； sigma non-opioid intracellular receptor 1； SR31747 binding protein 1； aging-associated gene 8 protein； sigma 1-type opioid receptor； 衰老相关Sigma受体蛋白；
背景信息：
This gene encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Mutations in this gene has been associated with juvenile amyotrophic lateral sclerosis 16. Alternative splicing of this gene results in transcript variants encoding distinct isoforms. [provided by RefSeq, Aug 2013]
