基因名:
CRISP3
产品别名:
Aeg2; CRISP-3; CRS3; SGP28; dJ442L6.3; CRISP3; cysteine rich secretory protein 3; cysteine rich secretory protein 3; cysteine-rich secretory protein 3; specific granule protein (28 kDa); 半胱氨酸丰富分泌蛋白3(CRISP3); 富含半胱氨酸分泌蛋白3;
背景信息:
Cysteine-rich secretory protein 3 (CRISP-3) is a secreted protein,containing 1 SCP domain and 1 ShKT domain.It is belongs to the CRISP family. CRISP-3 is a glycoprotein that belongs to the family of cysteine-rich secretory proteins (CRISPs) which was originally discovered in human neutrophilic granulocytes. CRISP-3 is also widely distibuted in exocrine glands (salivary glands, pancreas and prostate), eosinophilic granulocytes and to a lower level in epididymis, ovary, thymus and colon. The presence of CRISP-3 in neutrophils, eosinophils and in exocrine secretions indicates a role in innate host defense. The antibody has been raised against recombinant C-terminally truncated form of CRISP-3 and recognizes both the N-glycosylated and non-glycosylated form of the mature protein.