基因名：
BAIAP2
产品别名：
BAP2； FLAF3； IRSP53； WAML； BAIAP2； BAR/IMD domain containing adaptor protein 2； BAR/IMD domain containing adaptor protein 2； brain-specific angiogenesis inhibitor 1-associated protein 2； BAI1 associated protein 2； IRS-58； IRSp53/58； WASP and MIM like； fas ligand-associated factor 3； insulin receptor substrate of 53 kDa； insulin receptor substrate p53/p58； insulin receptor substrate protein of 53 kDa； 胰岛素受体底物p53蛋白；
背景信息：
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This interaction at the cytoplasmic membrane is crucial to the function of this protein, which may be involved in neuronal growth-cone guidance. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. Alternative splicing of the end of this gene results in three products of undetermined function.
