基因名:
PIBF1
产品别名:
C13orf24; CEP90; JBTS33; PIBF; PIBF1; progesterone immunomodulatory binding factor 1; progesterone immunomodulatory binding factor 1; progesterone-induced-blocking factor 1; centrosomal protein of 90 kDa; 孕激素诱导阻断因子; 孕酮免疫调节结合因子1(PIBF1); 孕酮诱导阻断因子1;
背景信息:
C13orf24 is also known as Progesterone-induced-blocking factor 1 (PIBF1). PIBF1 is synthesized by lymphocytes of healthy pregnant women in the presence of progesterone and inhibits arachidonic acid release, by acting on the phospholipase A2 enzyme, inducing a Th2 biased immune response. It also controls NK activity, and modifies the cytokine balance exerting an anti-abortive effect.