基因名：
PPIH
产品别名：
CYP-20； CYPH； SnuCyp-20； USA-CYP； PPIH； peptidylprolyl isomerase H； peptidylprolyl isomerase H； peptidyl-prolyl cis-trans isomerase H； PPIase h； U-snRNP-associated cyclophilin SnuCyp-20； U-snRNP-associated cyclophilin SunCyp-20； USA-CyP SnuCyp-20； cyclophilin H； rotamase H； small nuclear ribonucleoprotein particle-specific cyclophilin H；
背景信息：
Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins. PPIases can catalyze the cis-trans isomerization of Proline Imidic peptide bonds in oligopeptides. PPIH participates in pre-mRNA splicing. It is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. In addition, PPIH has PPIase activity and may play a role as a chaperone mediating the interactions between different proteins inside the spliceosome.
