基因名:
NCOA2
产品别名:
GRIP1; KAT13C; NCoA-2; SRC2; TIF2; bHLHe75; NCOA2; nuclear receptor coactivator 2; nuclear receptor coactivator 2; nuclear receptor coactivator 2; class E basic helix-loop-helix protein 75; glucocorticoid receptor-interacting protein-1; p160 steroid receptor coactivator 2; transcriptional intermediary factor 2; 磷酸化类固醇受体激活蛋白2; 类固醇受体激活蛋白2;
背景信息:
Steroid and thyroid hormones and retinoic acid regulate a complex array of gene expression activity via intracellular receptor transcription factors belonging to the ligand dependent nuclear receptor superfamily. Adding to the complexity of function of these transcription factors are associated proteins known as coactivators and corepressors which, as their names suggest, enhance or depress transcriptional activity of the nuclear receptor with which they associate. One such coactivator is KAT13C / nuclear receptor coactivator 2 (NCOA2), also termed Glucocorticoid receptor-interacting protein 1 (GRIP1).