基因名：
SEMA4D
产品别名：
A8； BB18； C9orf164； CD100； COLL4； GR3； M-sema-G； SEMAJ； coll-4； SEMA4D； semaphorin 4D； semaphorin 4D； semaphorin-4D； sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D； sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 4D； Semaphorin 4D/CD100蛋白； 信号素4D(SEMA4D)； 跨膜蛋白SEMA4D；
背景信息：
Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells, regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/PYK2, which then mediates activation of phosphatidylinositol 3-kinase and of the AKT1 signaling cascade.
