基因名:
TXNRD2
产品别名:
GCCD5; SELZ; TR; TR-BETA; TR3; TRXR2; TXNRD2; thioredoxin reductase 2; thioredoxin reductase 2; thioredoxin reductase 2, mitochondrial; selenoprotein Z; thioredoxin reductase 3; thioredoxin reductase TR3; thioredoxin reductase beta; 硒蛋白Z;
背景信息:
This gene encodes a member of the class I pyridine nucleotide-disulfide oxidoreductase family. The encoded protein is a selenocysteine-containing flavoenzyme that maintains thioredoxins in a reduced state, thereby playing a key role in regulating the cellular redox environment. Mammals have three related thioredoxin reductases. This gene encodes a mitochondrial form important for scavenging of reactive oxygen species in mitochondria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2013]