基因名：
MXD4
产品别名：
MAD4； MST149； MSTP149； bHLHc12； MXD4； MAX dimerization protein 4； MAX dimerization protein 4； max dimerization protein 4； Mad4 homolog； class C basic helix-loop-helix protein 12； max dimerizer 4； max-associated protein 4； max-interacting transcriptional repressor MAD4； MAD4蛋白；
背景信息：
This gene is a member of the MAD gene family . The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues. [provided by RefSeq, Jul 2008]
