基因名:
PMVK
产品别名:
HUMPMKI; PMK; PMKA; PMKASE; POROK1; PMVK; phosphomevalonate kinase; phosphomevalonate kinase; phosphomevalonate kinase; testis tissue sperm-binding protein Li 95mP; 磷酸甲羟戊酸激酶;
背景信息:
Phosphomevalonate kinase (PMVK) is a cytosolic enzyme. PMVK can be highly expressed in the heart,skeletal muscle, liver, pancreas, and kidney; it is expressed at lower levels in the brain, lung, and placenta. Induced by sterol, PMVK takes part in isopentenyl diphosphate biosynthesis through the mevalonate pathway. PMVK catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate in the fifth reaction of the cholesterol biosynthetic pathway.