基因名:
KLF1
产品别名:
EKLF; EKLF/KLF1; KLF1; KLF transcription factor 1; KLF transcription factor 1; Krueppel-like factor 1; Kruppel like factor 1; erythroid Kruppel-like factor; erythroid krueppel-like transcription factor; erythroid-specific transcription factor EKLF; Kruppel样因子1(KLF1); 上皮锌指蛋白1, 2, 4;
背景信息:
This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype. [provided by RefSeq, Oct 2009].