基因名:
DLL3
产品别名:
SCDO1; DLL3; delta like canonical Notch ligand 3; delta like canonical Notch ligand 3; delta-like protein 3; delta-like 3; delta3; drosophila Delta homolog 3; Notch信号通路Delta样配体3; δ样蛋白3(dLL3);
背景信息:
Delta-like 3 (Drosophila), also known as DLL3, is a protein which in humans is encoded by the DLL3 gene.Two transcript variants encoding distinct isoforms have been identified for this gene.Mutations in this gene cause the autosomal recessive genetic disorder Jarcho-Levin syndrome.Expression of the gene occurs in Neuroendocrine tumors, which has been targeted as a potential pathway for treatment.