基因名:
NFAT5
产品别名:
NF-AT5; NFATL1; NFATZ; OREBP; TONEBP; NFAT5; nuclear factor of activated T cells 5; nuclear factor of activated T cells 5; nuclear factor of activated T-cells 5; NFAT-like protein 1; T-cell transcription factor NFAT5; TonE-binding protein; glutamine rich protein H65; nuclear factor of activated T-cells 5, tonicity-responsive; osmotic response element-binding protein; tonicity-responsive enhancer-binding protein; 活化T细胞核因子5蛋白; 磷酸化活化T细胞核因子5蛋白;
背景信息:
The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene.