基因名：
MTHFD2
产品别名：
NMDMC； MTHFD2； methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase； methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase； bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial； NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase； 亚甲基四氢叶酸脱氢酶2；
背景信息：
This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7. [provided by RefSeq, Mar 2009]
