基因名：
MMP24
产品别名：
MMP-24； MMP25； MT-MMP 5； MT-MMP5； MT5-MMP； MT5MMP； MTMMP5； MMP24； matrix metallopeptidase 24； matrix metallopeptidase 24； matrix metalloproteinase-24； matrix metallopeptidase 24 (membrane-inserted)； matrix metalloproteinase 24 (membrane-inserted)； membrane-type 5 matrix metalloproteinase； membrane-type matrix metalloproteinase 5； 基质金属蛋白酶-24； 基质金属蛋白酶24(MMP24)；
背景信息：
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. [provided by RefSeq, Jul 2008]
