基因名：
DBF4
产品别名：
ASK； CHIF； DBF4A； ZDBF1； DBF4； DBF4 zinc finger； DBF4 zinc finger； protein DBF4 homolog A； DBF4 homolog； DBF4 zinc finger A； DBF4-type zinc finger-containing protein 1； activator of S phase kinase； chiffon homolog A； zinc finger, DBF-type containing 1； S期激酶活化蛋白DBF4A；
背景信息：
Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
Tissue specificity: Highly expressed in testis and thymus. Expressed also in most cancer cells lines.
