基因名:
APOBEC2
产品别名:
ARCD1; ARP1; APOBEC2; apolipoprotein B mRNA editing enzyme catalytic subunit 2; apolipoprotein B mRNA editing enzyme catalytic subunit 2; C->U-editing enzyme APOBEC-2; apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2; mRNA(cytosine(6666)) deaminase 2; probable C->U-editing enzyme APOBEC-2; 载脂蛋白B-mRNA编辑酶复合物2;
背景信息:
APOBEC2 is a 224 amino acid protein that belongs to the cytidine and deoxycytidylate deaminase family. Expressed exclusively in heart and skeletal muscle, APOBEC2 is thought to be a probable C (cytidine) to U (uridine) editing enzyme. However, unlike other members of the family, such as APOBEC1, which mediates the editing of apolipoprotein (apo) B mRNA, APOBEC2 does not display any detectable apoB mRNA editing activity. Also, APOBEC2 has been shown to have low, but definite, intrinsic cytidine deaminase activity.