基因名：
TMED10
产品别名：
P24(DELTA)； S31I125； S31III125； TMP21； Tmp-21-I； p23； p24d1； TMED10； transmembrane p24 trafficking protein 10； transmembrane p24 trafficking protein 10； transmembrane emp24 domain-containing protein 10； 21 kDa transmembrane trafficking protein； p24 family protein delta-1； p24delta； p24delta1； testicular tissue protein Li 206； transmembrane emp24-like trafficking protein 10； transmembrane protein Tmp21； 跨膜转运蛋白21；
背景信息：
TMP21 is a member of the EMP24/GP25L/p24 cargo family of proteins that regulates vesicular trafficking in the early secretory pathway. TMP21 is a ubiquitously expressed single-pass type I membrane protein localizing to the Golgi cisternae and the plasma membrane. It contains one GOLD (Golgi dynamics) domain and participates in protein transport and quality control between the endoplasmic reticulum (ER) and the Golgi complex. In addition, TMP21 is a component of the heteromeric secretase complex (or Presenilin complex) and functions to regulate the ?secretase activity. Two isoforms, namely TMP21-I and TMP21-II, exist for this protein.
