基因名：
FERMT2
产品别名：
KIND2； MIG2； PLEKHC1； UNC112； UNC112B； mig-2； FERMT2； FERM domain containing kindlin 2； FERM domain containing kindlin 2； fermitin family homolog 2； PH domain-containing family C member 1； fermitin family member 2； kindlin 2； mitogen inducible gene 2 protein； mitogen inducible gene-2； pleckstrin homology domain containing, family C (with FERM domain) member 1； pleckstrin homology domain containing, family C member 1； 丝裂原诱导蛋白2；
背景信息：
Mig-2 recruits migfilin to cell-matrix adhesions, while the interaction with filamin mediates the association of migfilin with actin filaments. Together, Mig-2, migfilin and filamin define a connection between cell matrix adhesions and the actin cytoskeleton and participate in the orchestration of actin assembly and cell shape modulation. Mig-2 expression is transcriptionally elevated in leiomyomas and could be involved in its hormone-mediated growth of leiomyomas of the uterus. Expression of Mig-2 is ubiquitous, and it is found in numerous tumor tissues.
