基因名:
TLK2
产品别名:
HsHPK; MRD57; PKU-ALPHA; TLK2; tousled like kinase 2; tousled like kinase 2; serine/threonine-protein kinase tousled-like 2; 丝氨酸/苏氨酸激酶TLK2;
背景信息:
Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly.
Tissue specificity: Widely expressed. Present in fetal placenta, liver, kidney, pancreas, heart and skeletal muscle. Also found in adult cell lines.