基因名:
LILRA1
产品别名:
CD85I; LIR-6; LIR6; LILRA1; leukocyte immunoglobulin like receptor A1; leukocyte immunoglobulin like receptor A1; leukocyte immunoglobulin-like receptor subfamily A member 1; CD85 antigen-like family member I; leucocyte Ig-like receptor A1; leukocyte immunoglobulin-like receptor 6; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1; 白细胞免疫球蛋白样受体6;
背景信息:
Leukocyte immunoglobulin-like receptors (LILRs) are inhibitory, stimulatory or soluble receptors encoded within the leukocyte receptor complex. Some LILRs are extensively polymorphic, and exhibit evidence for balancing selection and association with disease susceptibility. LILRA1 (LIR-6) can recognize MHC (major histocompatibility complex) class I or class I-like molecules, and high levels of sequence similarity among LILRA1, LILRA2 (ILT1), LILRA3 (ILT6) and LILRB1/B2.