基因名：
PNKP
产品别名：
AOA4； CMT2B2； EIEE10； MCSZ； PNK； PNKP； polynucleotide kinase 3'-phosphatase； polynucleotide kinase 3'-phosphatase； bifunctional polynucleotide phosphatase/kinase； DNA 5'-kinase/3'-phosphatase； Homo sapiens polynucleotide kinase 3'-phosphatase (PNKP)； 多聚合苷酸激酶3磷酸化酶；
背景信息：
Mammalian PNK catalyzes the phosphorylation of DNA at 5'-hydroxyl termini and can dephosphorylate its 3'-phosphate termini. It plays an important function in DNA repair following ionizing radiation or oxidative damage. PNK has been reported to participate in the repair of DNA-double strand breaks via PARP-1-dependent nonhomologous end-joining.
