基因名：
Cd2ap
产品别名：
AL024079； C78928； METS-1； Mets1； Cd2ap； CD2-associated protein； CD2-associated protein； CD2-associated protein； SH3 domain-containing adapter protein； SH3 domain-containing adaptor protein METS-1； mesenchyme to epithelium transition protein, SH3 domains； mesenchyme-to-epithelium transition protein with SH3 domains 1； CD2关联蛋白(CD2AP)； 白细胞分化抗原CD2AP；
背景信息：
This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease. [provided by RefSeq, Jul 2008].
