基因名：
Ccr2
产品别名：
Cc-ckr-2； Ccr2a； Ccr2b； Ckr2； Ckr2a； Ckr2b； Cmkbr2； mJe-r； Ccr2； chemokine (C-C motif) receptor 2； chemokine (C-C motif) receptor 2； C-C chemokine receptor type 2； C-C CHEMOKINE RECEPTOR TYPE 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC RECEPTOR) (MCP-1 RECEPTOR)； C-C CKR-2； CCR-2； JE/FIC receptor； MCP-1 receptor； MIP-1 alphaR； chemoattractant protein-1 receptor； chemokine (C-C) receptor 2； 细胞表面趋化因子受体2； 细胞表面趋化因子受体2A； 趋化因子C-C-基元受体2(CCR2)；
背景信息：
This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene. [provided by RefSeq, Mar 2009].
