基因名：
Itln1
产品别名：
IntL； Itln； Itln2； Itln3； Itln5； Itlna； Lfr； Itln1； intelectin 1 (galactofuranose binding)； intelectin 1 (galactofuranose binding)； intelectin-1a； calcium-dependent galactosyl-specific lectin； galactofuranose-binding lectin； intelectin 2； intelectin 5； intelectin a； intestinal lactoferrin receptor； 内凝集蛋白1(ITLN1)； 内皮细胞凝集素HL1；
背景信息：
Intelectin-1(ITLN1) is a secreted protein and contains 1 fibrinogen C-terminal domain. Intelectin-1 is a 40 kDa Ca-dependent galactofuranose-binding lectin that is not a C-type lectin. It is expressed on multiple cell types and appears to participate in insulin signaling and microbe recognition. The protein has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. It increases AKT phosphorylation in the absence and presence of insulin and it may play a role in the defense systemagainst microorganisms. It also may specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosy l residues, in a calcium-dependent manner.
