基因名:
Klf3
产品别名:
9930027G08Rik; AL024007; Bklf; Tef-2; Klf3; Kruppel-like factor 3 (basic); Kruppel-like factor 3 (basic); Krueppel-like factor 3; CACCC-box-binding protein BKLF; basic krueppel-like factor; 锌指蛋白741;
背景信息:
KLF3 is a transcriptional repressor and activator. It also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G phase as a downstream target of focal adhesion kinase (FAK). Ubiquitously expressed. Kruppel-like factor proteins all contain a characteristic C-terminal DNA binding domain containing 3 Kruppel-like zinc fingers, and they all recognize CACCC and GC boxes present in promoters and enhancers.