基因名：
Mrpl40
产品别名：
Nlvcf； Mrpl40； mitochondrial ribosomal protein L40； mitochondrial ribosomal protein L40； 39S ribosomal protein L40, mitochondrial； L40mt； MRP-L40； nuclear localization signal protein absent in velo-cardio-facial patients； nuclear localization signal-containing protein deleted in velocardiofacial syndrome homolog； 线粒体核糖体蛋白L40；
背景信息：
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome. [provided by RefSeq, Jul 2008]
