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重组核蛋白95
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

Recombinant Uhrf1
Recombinant ubiquitin-like, containing PHD and RING finger domains, 1 protein
基因名:

Uhrf1


产品别名:

AL022808; ICBP90; Np95; RNF106; Uhrf1; ubiquitin-like, containing PHD and RING finger domains, 1; ubiquitin-like, containing PHD and RING finger domains, 1; E3 ubiquitin-protein ligase UHRF1; RING-type E3 ubiquitin transferase UHRF1; mUhrf1; nuclear protein 95; nuclear zinc finger protein Np95; ubiquitin-like PHD and RING finger domain-containing protein 1; ubiquitin-like-containing PHD and RING finger domains protein 1; 核蛋白95;


背景信息:
Putative E3 ubiquitin-protein ligase. May participate in methylation-dependent transcriptional regulation. Binds to inverted 5'-CCAAT-3' box 2 in the TOP2A promoter, and activates TOP2A expression. Important for G1/S transition. May be involved in DNA repair and chromosomal stability.
Tissue specificity:Expressed in thymus, bone marrow, testis, lung and heart. Overexpressed in breast cancer.
 
 
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