基因名：
Padi4
产品别名：
Pad4； Pdi4； Padi4； peptidyl arginine deiminase, type IV； peptidyl arginine deiminase, type IV； protein-arginine deiminase type-4； PAD type IV； peptidylarginine deiminase IV； protein-arginine deiminase type IV； 关节炎相关基因； 肽基精氨酸脱亚氨酶Ⅳ(PADI4)；
背景信息：
Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyzes the citrullination/deimination of arginine residues of proteins. In addition, PADI4 may play an important role in tumourigenesis. Genetic variations in PADI4 are a cause of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and a complex genetic component.
