基因名:
Ppp1r1b
产品别名:
AU040756; DARPP-32; Darpp32; Ppp1r1b; protein phosphatase 1, regulatory inhibitor subunit 1B; protein phosphatase 1, regulatory inhibitor subunit 1B; protein phosphatase 1 regulatory subunit 1B; dopamine- and cAMP-regulated neuronal phosphoprotein; 多巴胺、cAMP调节磷蛋白; 磷酸化多巴胺/cAMP调节磷蛋白; 磷酸化多巴胺/cAMP调节神经磷蛋白; 蛋白磷酸酶1调节因子亚基1B(PPP1R1B);
背景信息:
This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].