基因名:
Ccl6
产品别名:
MRP-1; Scya6; c10; Ccl6; chemokine (C-C motif) ligand 6; chemokine (C-C motif) ligand 6; C-C motif chemokine 6; CC chemokine C10; small-inducible cytokine A6; 嗜酸粒细胞趋化蛋白CCL6; 趋化因子C-C基元配体6(CCL6);
背景信息:
CCL6 (C10) is a small cytokine belonging to the CC chemokine family that has only been identified in rodents. It is a potent chemoattractant of macrophages, but it can also attract B cells, CD4+ lymphocytes and eosinophils. In mice, CCL6 is expressed in cells from neutrophil and macrophage lineages, and can be induced under conditions suitable for myeloid cell differentiation. CCL6 (C10) was originally identified as a transcript that is induced in bone marrow cells upon stimulation of GMCSF. The cell surface receptor for CCL6 is believed to be the chemokine receptor CCR1.