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重组巨噬细胞炎症蛋白-1γ
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

Recombinant Ccl9
Recombinant chemokine (C-C motif) ligand 9 protein
基因名:

Ccl9


产品别名:

CCF18; MRP-2; Scya10; Scya9; Ccl9; chemokine (C-C motif) ligand 9; chemokine (C-C motif) ligand 9; C-C motif chemokine 9; MIP-1 gamma; macrophage inflammatory protein 1-gamma; macrophage inflammatory protein-related protein 2; small inducible cytokine A10; small inducible cytokine A9; 巨噬细胞炎症蛋白-1γ;


背景信息:
C-C motif chemokine 9(CCL9) is an 11 kDa, secreted, monomeric polypeptide that belongs to the beta (or CC) intercrine family of chemokines. It is expressed mainly in the liver, lung, and the thymus, although some expression has been detected in a wide variety of tissues except brain. Monokine has inflammatory, pyrogenic and chemokinetic properties. It circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor,it activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitors. CCL9 can activate osteoclasts through its receptor CCR1 (the most abundant chemokine receptor found on osteoclasts) suggesting an important role for CCL9 in bone resorption.
 
 
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