基因名:
Tcf7l1
产品别名:
Tcf-3; Tcf3; bHLHb21; Tcf7l1; transcription factor 7 like 1 (T cell specific, HMG box); transcription factor 7 like 1 (T cell specific, HMG box); transcription factor 7-like 1; HMG box transcription factor 3; T-cell factor 3; transcription factor 3; transcription factor 7-like 2 (T-cell specific, HMG box); 转录因子7样蛋白1;
背景信息:
This gene encodes a member of the T cell factor/lymphoid enhancer factor family of transcription factors. These transcription factors are activated by beta catenin, mediate the Wnt signaling pathway and are antagonized by the transforming growth factor beta signaling pathway. The encoded protein contains a high mobility group-box DNA binding domain and participates in the regulation of cell cycle genes and cellular senescence. [provided by RefSeq, Nov 2010]