基因名：
Lin7c
产品别名：
9130007B12Rik； AI303698； AU019331； AW125731； D2Ertd520e； LIN-7-C； LIN-7C； MALS-3； Veli3； Lin7c； lin-7 homolog C, crumbs cell polarity complex component； lin-7 homolog C, crumbs cell polarity complex component； protein lin-7 homolog C； lin 7 homolog c； lin-7 homolog C； mLin7C； mammalian lin-seven protein 3； veli-3； vertebrate homolog of C. elegans Lin-7 type 3； vertebrate lin-7 homolog 3； LIN7C蛋白；
背景信息：
Velis are a family of small synaptic proteins that interact with other proteins at the post-synaptic density (PSD) of neuronal synapses. Velis contain the PDZ motif involved in recruiting cell adhesion molecules, receptors, and channels. Veli1 (also designated Lin-7A and MALS-1), Veli2 (also designated Lin-7B and MALS-2), and Veli3 (also designated Lin-7C and MALS-3) are mammalian homologs of C. elegans LIN-7. Veli proteins are ubiquitously expressed with high expression in brain, liver, and testis. Velis are localized at the synaptic junctions in neurons. Velis bind to CASK, a neurexin-binding protein highly concentrated in synapses, and Mint1, a binding partner with a vesicle trafficking protein.
