基因名：
SIRT2
产品别名：
SIR2； SIR2L； SIR2L2； SIRT2； sirtuin 2； sirtuin 2； NAD-dependent protein deacetylase sirtuin-2； NAD-dependent deacetylase sirtuin-2； NAD-dependent protein defatty-acylase sirtuin-2； SIR2-like protein 2； regulatory protein SIR2 homolog 2； silent information regulator 2； sir2-related protein type 2； sirtuin type 2； 沉默调节相关蛋白2； 沉默调节蛋白2(SIRT2)；
背景信息：
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene. [provided by RefSeq, Jul 2010]
