基因名:
SCMH1
产品别名:
Scml3; SCMH1; Scm polycomb group protein homolog 1; Scm polycomb group protein homolog 1; polycomb protein SCMH1; sex comb on midleg homolog 1; 多梳蛋白SCMH1;
背景信息:
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.