基因名：
DAAM1
产品别名：
DAAM1； dishevelled associated activator of morphogenesis 1； dishevelled associated activator of morphogenesis 1； disheveled-associated activator of morphogenesis 1； 形态发生紊乱关联激活因子1； 磷酸化形态发生紊乱关联激活因子1； 蓬乱蛋白关联形态激活因子1(DAAM1)；
背景信息：
DAAM1 (Dishevelled associated activator of morphogenesis 1) is a diaphanous-related formin which binds to dishevelled (Dvl) and Rho, and mediates Wnt-induced Dvl-Rho complex assembly. It is an essential component of noncanonical Wnt signaling. DAAM1 also communicates with Rho GTPases, CIP4 and Src in the regulation of the signalling pathways that co-ordinate the dynamics of the actin filament system. DAAM1 may be a coordinator of endocytosis and cytoskeletal remodeling.
