基因名:
EXOSC7
产品别名:
EAP1; RRP42; Rrp42p; hRrp42p; p8; EXOSC7; exosome component 7; exosome component 7; exosome complex component RRP42; exosome complex exonuclease RRP42; ribosomal RNA-processing protein 42; 核糖体RNA合成蛋白42;
背景信息:
The exosome is a multisubunit complex of 3’ to 5’ exoribonucleases. It is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich elements in their untranslated 3’ region. EXOSC7 (exosome component 7), also known as p8, EAP1, RRP42 (Ribosomal RNA-processing protein 42), Rrp42p or hRrp42p, is a component of the exosome multienzyme ribonuclease complex. It belongs to the RNase PH family and localizes to the nucleolus. EXOSC7 is one of the six RNase-PH domain subunits of the exosome. Together, these six subunits form a PNPase-like ring. EXOSC7 is required for the processing of the 7S pre-RNA.