基因名:
SMC5
产品别名:
SMC5L1; SMC5; structural maintenance of chromosomes 5; structural maintenance of chromosomes 5; structural maintenance of chromosomes protein 5; SMC protein 5; SMC-5; SMC5 structural maintenance of chromosomes 5-like 1; hSMC5; 染色体结构维持蛋白5;
背景信息:
Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. The chromosome proteins are conserved in eukaryotes lead to mitotic chromosome segregation defects, suggesting a critical function of SMC family proteins in mitotic chromosome dynamics.