基因名：
RTF1
产品别名：
GTL7； KIAA0252； RTF1； RTF1 homolog, Paf1/RNA polymerase II complex component； RTF1 homolog, Paf1/RNA polymerase II complex component； RNA polymerase-associated protein RTF1 homolog； Rtf1, Paf1/RNA polymerase II complex component, homolog； ortholog of mouse gene trap locus 7； 组织相容性复合物RTF1；
背景信息：
RTF1 is the the major histocompatibility complex (MHC) in the rat which contains genes that code for two class II histocompatibility antigens. RT1-B is an antigen of the RT1 complex. It is a protein dimer consisting of an alpha and beta glycoprotein chain and is homologous to I-A and I-E genes, respectively, in the H-2 complex of the mouse. MHC Class II antigens are useful in studying T helper cell interaction with class II positive antigen presenting cells (dendritic cells, B cells, macrophages) and offer new possibilities for studying the development of T helper cells since these antibodies also stain stromal cells in the thymus.
