基因名：
FBXW11
产品别名：
BTRC2； BTRCP2； FBW1B； FBXW1B； Fbw11； Hos； NEDJED； FBXW11； F-box and WD repeat domain containing 11； F-box and WD repeat domain containing 11； F-box/WD repeat-containing protein 11； F-box and WD repeats protein beta-TrCP2； F-box and WD-40 domain protein 11； F-box and WD-40 domain protein 1B； F-box protein Fbw1b； F-box/WD repeat-containing protein 1B； beta-transducin repeat-containing protein 2； homologous to Slimb protein； BTRC2蛋白；
背景信息：
Beta TRCP2 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.
