SFOM-0046 is an anticancer agent. It arrests the cell cycle in S-phase and causes DNA replication stress, leading to the phosphorylation of H2AX into gamma-H2AX. References: Pauty J, Coté MF, Rodrigue A, Velic D, Masson JY, Fortin S. Investigation of the DNA damage response to SFOM-0046, a new small-molecule drug inducing DNA double-strand breaks. Sci Rep. 2016 Mar 22;6:23302. doi: 10.1038/srep23302. PubMed PMID: 27001483; PubMed Central PMCID: PMC4802344.

纯度：≥98%

CAS：1383607-61-1