基因名:
EXOSC2
产品别名:
RRP4; Rrp4p; SHRF; hRrp4p; p7; EXOSC2; exosome component 2; exosome component 2; exosome complex component RRP4; exosome complex exonuclease RRP4; homolog of yeast RRP4 (ribosomal RNA processing 4), 3' 5' exoribonuclease (RRP4); homolog of yeast RRP4 (ribosomal RNA processing 4), 3'-5'-exoribonuclease; ribosomal RNA-processing protein 4; RRP4蛋白; 外切酶体成分2(EXOSC2);
背景信息:
Rrp4 and Ski7p are components of the cytoplasmic exosome complex, and together with the RNA helicase Ski2p they are necessary for degradation of deadenylated mRNA. Rrp4 is required for the 3’ to 5’ exonuclease activity that produces the 3’ end of the 5.8S rRNA. Rrp4 also functions as a subunit of the specialized trypanosome exosome complex.