基因名:
COTL1
产品别名:
CLP; COTL1; coactosin like F-actin binding protein 1; coactosin like F-actin binding protein 1; coactosin-like protein; coactosin-like 1; epididymis secretory sperm binding protein; 毛状样蛋白1(COTL1); 肌动蛋白辅助蛋白类样蛋白;
背景信息:
This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes. [provided by RefSeq, Jul 2008]