重组剪接体相关蛋白155

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重组剪接体相关蛋白155

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

重组剪接因子3B亚基1(SF3B1)蛋白
Recombinant SF3B1

基因名：

SF3B1

产品别名：

Hsh155； MDS； PRP10； PRPF10； SAP155； SF3b155； SF3B1； splicing factor 3b subunit 1； splicing factor 3b subunit 1； splicing factor 3B subunit 1； pre-mRNA processing 10； pre-mRNA splicing factor SF3b, 155 kDa subunit； spliceosome-associated protein 155； splicing factor 3b, subunit 1, 155kDa；剪接体相关蛋白155；剪接因子3B亚基1(SF3B1)；

背景信息：

SAP 155 is a 1,304 amino acid member of the SF3B1 family and contains eleven HEAT repeats. Localized to nuclear speckles and also to the cytoplasm during mitosis, SAP 155 is a subunit of the SF3B splicing factor. The SF3B splicing factor is a U2 snRNP-associated protein complex essential for spliceosome assembly. SF3B contains the spliceosomal proteins SAP 49, SAP 130, SAP 145 and SAP 155. Concomitant with splicing catalysis, SAP 155 is phosphorylated at its N-terminal Thr-Pro dipeptide motifs by Dyrk1A and cyclin E/Cdk2. This modification of SAP 155 is vital for a functional spliceosome as it is an essential event in the basic splicing reaction. Due to alternative splicing events, various SAP 155 isoforms are produced.

标签：His-tag
分类：Recombinant
类型：Protein
偶联物：Unconjugated
内毒素水平：按批次，参阅瓶身标签
性状:Liquid
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型：purified
内含物：不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存：2-8°C不超过一个月，-80°C不超过12个月。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。