基因名:
PES1
产品别名:
NOP7; PES; PES1; pescadillo ribosomal biogenesis factor 1; pescadillo ribosomal biogenesis factor 1; pescadillo homolog; pescadillo homolog 1, containing BRCT domain; Pescadillo同源物1(PES1);
背景信息:
Pescadillo may play a crucial role in cell proliferation and may be necessary for oncogenic transformation and tumor progression. The protein is abnormally elevated in malignant tumors of astrocytic origin. It is a strongly conserved gene containing a BRCT domain that is essential for the activity of this gene product.